Poly (Lactic Acid)Nanofibres as Drug Delivery Systems: Opportunities and Challenges

Nanotechnology systems for oral drug delivery: challenges and opportunities

Multiprotein Systems As Targets for Drug Discovery: Opportunities and Challenges

In the past twenty years structural biology has come to play a major role in lead optimization and target identification in the process of drug discovery. Only recently, however, has the development of highthroughput methods of structure determination provided a powerful approach to the screening of fragment binding so that structural biology can now contribute directly to lead discovery. Most ...

Pluronic as nano-carier for drug delivery systems

A common approach for building a drug delivery system is to incorporate the drug within the nanocarrier that results in increased solubility, metabolic stability, and improved circulation time. However, recent developments indicate that selection of polymer nanomaterials can implement more than only inert carrier functions by being biological response modifiers. One representative of such mater...

Nanophase Ceramics for Improved Drug Delivery: Current Opportunities and Challenges

Introduction After more than a decade of research and development, nanotechnology has reshaped the traditional thinking (or lack thereof) of using ceramics for drug delivery. Although drug delivery has been a polymer-dominated field, the blossoming of nanotechnology means that ceramic materials are now showing much promise for numerous drug delivery applications. Typically, nanotechnology is de...

Cancer Therapeutics- Opportunities, Challenges and Advances in Drug Delivery

This review highlights the characteristics of the cancer that provide opportunities for drug delivery carriers to target cancer. These opportunities include EPR effect, high interstitial pressure of tumour, low pH of endosomes of tumor cells, overexpressed receptors, angiogenesis etc. Chemotherapy is one of the most important treatments currently available among the various approaches. The pres...

Kidney-Specific Drug Delivery: Review of Opportunities, Achievements, and Challenges

Kidneys are involved in essential complex procedures that maintain the body in equilibrium and preservethe interior environment necessary for life. Nephritis and nephrosis were ranked among the leading causes of death in all ages in the last global burden of disease assessment of the World Health Organization (WHO). Regarding kidney disease therapeutics, the unfavourable extra-target effects, t...